Ratios of CD64 expressed on neutrophils, monocytes, and lymphocytes may be a novel method for diagnosis of neonatal sepsis

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Ratios of CD64 expressed on neutrophils, monocytes, and lymphocytes may be a novel method for diagnosis of neonatal sepsis.

INTRODUCTION Neutrophil CD64 expression has been demonstrated as an improved diagnostic marker of infection and sepsis. The purpose of this study was to develop a new method to evaluate neutrophil CD64 expression for diagnosis of neonatal sepsis. METHODOLOGY Eighty neonates with neonatal sepsis (21 culture positive, 59 negative) were enrolled in this prospective study along with 19 neonates w...

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Evaluation of CD64 Expression on Peripheral Blood Neutrophils for Early Detection of Neonatal Sepsis

Background: Neonatal sepsis is a life-threatening disease with an incidence of 1 to 10 per 1000 live births and a mortality rate of 15% to 50%. The clinical signs are non-specific and indistinguishable from those caused by a variety of neonatal noninfectious disorders. Objective: The aim of this study was to determine the importance of CD64 expression (FcgRI), a neutrophil surface marker, in ea...

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CD64 cell surface expression on neutrophils for diagnosis of neonatal sepsis.

Neonatal sepsis (NS) continues to be one of the most significant causes of neonatal morbidity and mortality. Early identification of Neonatal sepsis is a major diagnostic problem because of the nonspecific clinical signs and limitations of the current diagnostic procedures. Neutrophil CD64 expression has been proposed as a diagnostic test for evaluation of infection and sepsis. We compared the ...

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evaluation of cd64 expression on peripheral blood neutrophils for early detection of neonatal sepsis

background: neonatal sepsis is a life-threatening disease with an incidence of 1 to 10 per 1000 live births and a mortality rate of 15% to 50%. the clinical signs are non-specific and indistinguishable from those caused by a variety of neonatal noninfectious disorders. objective: the aim of this study was to determine the importance of cd64 expression (fcgri), a neutrophil surface marker, in ea...

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Procalcitonin: A Reliable Marker for the Diagnosis of Neonatal Sepsis

Objective(s) In the last few years, serum procalcitonin has been proposed as an early marker of infections in neonates, with varying results. In this study, we aimed to investigate the value of procalcitonin, and C- reactive protein in establishing the diagnosis of neonatal sepsis. Materials and Methods Blood samples were collected at admission from 69 neonates with suspected infection (admi...

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ژورنال

عنوان ژورنال: The Journal of Infection in Developing Countries

سال: 2015

ISSN: 1972-2680

DOI: 10.3855/jidc.4992